Three-dimensional systems for in vitro follicular culture: overview of alginate-based matrices. Three-dimensional systems for in vitro follicular culture: overview of alginate-based matrices. Reprod Fertil Dev. 2013 Jul 19; Authors: Brito IR, Lima IM, Xu M, Shea LD, Woodruff TK, Figueiredo JR PMID: 23866836 [PubMed - as supplied by publisher] Original Article