Woodruff Lab is a pioneering research laboratory at focusing on reproductive science, women’s health, and fertility preservation. The lab is led by Dr. Teresa K. Woodruff, internationally recognized for her innovative contributions to reproductive biology, particularly in the context of oncofertility—the intersection of oncology and fertility preservation.
Lab Research Areas
Ovarian Follicle Development
The lab investigates the structure-function relationships of ovarian follicles, aiming to understand how these units develop and respond to hormonal signals. This research is crucial for advancing fertility preservation techniques and improving patient care
Oncofertility
Dr. Woodruff coined the term “oncofertility” in 2006 to describe the merging of oncology and fertility preservation. The Oncofertility Consortium, founded by Dr. Woodruff, is an international initiative that addresses the reproductive health challenges faced by young cancer patients. The consortium includes members from 117 countries and focuses on expanding fertility options for cancer survivors.
Environmental Research
The lab explores the impact of environmental contaminants, such as metals, on reproductive health. Through initiatives like the Northwestern University Superfund Research Center in Reproductive Health Hazards, the team aims to develop bioassays to assess reproductive toxicity and inform policy changes.
Innovative Models and Technologies
The Woodruff Lab has developed advanced models like EVATAR, a microfluidic system that simulates the human reproductive tract and menstrual cycle. Additionally, the lab has created decellularized and 3D-printed ovarian bioprosthetics, which have shown promise in restoring ovarian function in animal models.
Educational and Policy Initiatives
The lab is committed to advancing education in reproductive health through innovative programs. Dr. Woodruff has collaborated with educators and animators to create educational materials, such as animated videos, to teach students about puberty and reproductive anatomy. Additionally, the lab engages in policy advocacy to update guidelines on reproductive toxicity, aiming to influence institutions like the U.S. Environmental Protection Agency.