Ensuring that people with cancer understand how cancer treatment could affect their fertility and what options are available for preserving fertility were widely recognized as top priorities by attendees of the 2016 Oncofertility Conference in Chicago. As detailed at the conference, means of achieving those priorities include building a rapid-response multidisciplinary team, presenting patient information about fertility preservation in understandable and age-appropriate formats, and changing practice patterns so that fertility preservation options are addressed and initiated early.