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Sexual Health, Fertility, and Intimacy in Adolescent Cancer Patients

Adolescent and young adult cancer patients face unique social, physical, and emotional experiences during diagnosis and treatment that may not occur in younger or older individuals. A recent chapter in the book, Oncofertility Communication: Sharing Information and Building Relationships across Disciplines,…
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Oncofertility: Education and the Role of Decision-Making Tools

Education materials, whether in print or web-based, have a large role in helping patients feel confident in their medical decision-making.  Continuing with our overview of Oncofertility Communication: Sharing Information and Building Relationships across Disciplines, Chapter 3 focuses on the importance of education, and…
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Announcing new Book on Oncofertility Communication: Sharing Information and Building Relationships across Disciplines

Since the initiation of the “war on cancer” with the National Cancer Act in 1971, cancer survivorship has increased dramatically. As such survivors, especially young ones, frequently live many decades beyond their initial cancer diagnosis. With the escalating numbers of cancer…
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Yoga for Menopause

Hormone replacement therapy is one of the most well-evidenced and regulatory-approved treatment options for menopause, but what about natural alternatives? Many women turn to yoga to treat menopause symptoms, but new research has shown its benefits are limited. A randomized control study,…
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Research Update: First Live Human Birth From Vitrified Ovarian Tissue

The reproductive community took note recently with the publication of research stating that ovarian tissue cryopreserved using a technique called vitrification, has resulted in a live human birth. Ovarian tissue cryopreservation is an experimental fertility preservation technique that involves the surgical…
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First Conference of Society for Adolescent and Young Adult Oncology

The Society for Adolescent and Young Adult Oncology was founded to engage professionals who are dedicated to improving adolescent and young adult cancer care across the world. It promotes interdisciplinary research, education, and collaboration in order to advance understanding of the…
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Weight Management v. Weight Loss: Why Some Women Respond to the Former and Not the Latter

A recent study published by researchers at Duke University highlighted the fact that some populations of women are more receptive to weight-management interventions than programs advertising weight loss. Weight loss is difficult across all populations and many programs aimed at reducing…
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In Vitro Grown Ovarian Follicles from Cancer Patients Support Oocyte Growth

Fertility preservation options are necessary for young female cancer patients facing life-preserving but fertility-threatening treatments. Developing a method for in vitro growth of ovarian follicles may provide a future fertility preservation method. We demonstrate 30-day in vitro growth of secondary ovarian follicles isolated from cancer patients, which supports the notion that human follicle development can be achieved in a bio-engineered…
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Egg Zinc Sparks: Triggered by Fertilization and Facilitate Cell Cycle Resumption

Using probes, we show that fertilization of mature, zinc-enriched eggs trigger the ejection of zinc into the extracellular milieu as zinc sparks. The sparks mediate a decrease in intracellular zinc content that is necessary for continued cell cycle progression. The mammalian egg thus uses a…
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Primate Primordial Follicles Require a Rigid Environment to Grow in Vitro

Learn about the conditions developed to support culture of primordial follicles from primates. Using biomaterials, we mimic the rigidity of the ovarian environment, which lays the foundation for studying the basic biology of primordial follicles in a controlled environment and for…
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Rescue of Platinum-Damaged Oocytes Through p53 Family Inactivation

This work identifies the mechanism of the c-Abl kinase inhibitor imatinib mesylate, which has recently been identified as a fertoprotective agent against the alkylating chemotherapy cisplatin. We show that, in vitro, imatinib prevents cisplatin-induced apoptosis of oocytes within primordial follicles by inhibiting c-Able kinase and downstream…
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