March 2017

Publication in PNAS

Dr. Francesca Duncan and her colleagues recently published in the Proceedings of the National Academy of Sciences (PNAS). 

This paper "mTORC1/2 Inhibition Preserves Ovarian Function and Fertility during Genotoxic Chemotherapy" is significant for the following reasons: "A major unresolved issue for premenopausal women undergoing chemotherapy is infertility due to the loss of nonrenewable ovarian primordial follicles. We show that pharmacologic down-regulation of the mammalian/mechanistic target of rapamycin (mTOR) pathway during chemotherapy in a mouse model prevents activation of primordial follicles, preserves ovarian function, and maintains normal fertility using clinically available inhibitors of mTOR complex (C)1 and mTORC1/2. These findings represent a feasible pharmacologic approach for preservation of ovarian function and fertility during treatment with conventional chemotherapy."

New Report in Toxicological Sciences

Drs. Teresa Woodruff and Shuo Xiao recently published in Toxicological Sciences, which is one of the top journals in toxicology field. This paper examined doxorubicin and its effect on follicle function and oocyte health. Here is more information about the paper from its author Dr. Shuo Xiao:

Watch the March VGR Now!

The March VGR is now available online. Dr. Nao Suzuki presented an overview of the Japan Society for Fertility Preservation. His talk focused on the need for fertility preservation in Japan and history of JSFP. He also included an impressive array of the JSFP programs and the seminars they have hosted since their inception. JSFP is one of the most active Oncofertility Global Partners and we applaud them on all of their efforts. Click here to watch the presentation in its entirety. 

Dr. Jhenifer Rodrigues will deliver the April VGR and give updates from Brazil and Latin America!

Stay tuned for the announcement of the May 2017-June 2018 VGR Series. 

LIVESTRONG launches new online training

LIVESTRONG has launched a dynamic online training for health professionals focused on issues related to cancer treatment and fertility.

Even though more than 150,000 people diagnosed with cancer during their reproductive years, studies have found that health care professionals are still not informing nor referring patients to fertility preservation services at an acceptable rate. The LIVESTRONG Fertility Training for Healthcare Professionals was created to address this issue. The training helps health care providers: