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Role of androgens in testicular tumor development in inhibin-deficient mice.

Role of androgens in testicular tumor development in inhibin-deficient mice. Endocrinology. 1997 Nov;138(11):5000-5 Authors: Shou W, Woodruff TK, Matzuk MM To understand gonadal tumor development, we have previously created a mouse model in which mice deficient in the inhibins develop gonadal sex cord-stromal tumors with essentially 100% penetrance. These tumors develop as early as 4 weeks of age…

High levels of fetal membrane activin beta A and activin receptor IIB mRNAs and augmented concentration of amniotic fluid activin A in women in term or preterm labor.

High levels of fetal membrane activin beta A and activin receptor IIB mRNAs and augmented concentration of amniotic fluid activin A in women in term or preterm labor. J Endocrinol. 1997 Jul;154(1):95-101 Authors: Petraglia F, Di Blasio AM, Florio P, Gallo R, Genazzani AR, Woodruff TK, Vale W The aim of the present study was to evaluate whether…

The uterine myometrium is a target for increased levels of activin A during pregnancy

The uterine myometrium is a target for increased levels of activin A during pregnancy Endocrinology. 1997 Jul;138(7):3042-6 Authors: Draper LB, Chong H, Wang E, Woodruff TK Abstract: Activin A is a dimeric protein hormone that regulates numerous cellular functions. A clear physiological role for this molecule in pregnancy is suggested by previous studies in the human, wherein activin A rises…