Ultrasound Shear Wave Velocity Varies Across Anatomical Region in Ex Vivo Bovine Ovaries.
Tissue Eng Part A. 2020 Jun 30;:
Authors: Gargus ES, Jakubowski KL, Arenas GA, Miller SJ, Lee SSM, Woodruff TK
Abstract
The physical properties of the ovarian extracellular matrix (ECM) regulate the function of ovarian cells, specifically the…
Installing oncofertility programs for common cancers in limited resource settings (Repro-Can-OPEN Study): An extrapolation during the global crisis of Coronavirus (COVID-19) pandemic.
J Assist Reprod Genet. 2020 Jun 27;:
Authors: Salama M, Ataman-Millhouse L, Braham M, Berjeb K, Khrouf M, Rodrigues JK, Reis FM, Silva TC, Sánchez F, Romero S, Smitz J, Vásquez L, Vega M, Sobral…
Zinc Dynamics during Drosophila Oocyte Maturation and Egg Activation.
iScience. 2020 Jun 16;23(7):101275
Authors: Hu Q, Duncan FE, Nowakowski AB, Antipova OA, Woodruff TK, O'Halloran TV, Wolfner MF
Abstract
Temporal fluctuations in zinc concentration are essential signals, including during oogenesis and early embryogenesis. In mammals, zinc accumulation and release are required…
Good news on the active management of pregnant cancer patients.
F1000Res. 2020;9:
Authors: Folsom SM, Woodruff TK
Abstract
Cancer occurs in approximately 1/1000 to 1/2000 pregnancies and presents complex medical and ethical dilemmas for patients and providers. The most common cancers diagnosed in the gestational period include breast, cervical, melanoma, and…
Testicular organoid formation is a property of immature somatic cells, which self-assemble and exhibit long-term hormone-responsive endocrine function.
Biofabrication. 2020 Jun 03;:
Authors: Edmonds ME, Woodruff TK
Abstract
Testicular organoid models are tools to study testicular physiology, development, and spermatogenesisin vitro. However, few side-by-side comparisons of organoid generation method have been…
Counseling and surveillance of obstetric risks for female childhood, adolescent, and young adult cancer survivors: recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group.
Am J Obstet Gynecol. 2020 Jun 02;:
Authors: van der Kooi ALF, Mulder RL, Hudson MM, Kremer LCM, Skinner R, Constine LS, van Dorp W, van Dulmen-den Broeder E, Winther…
Oncofertility: Knowledge, Attitudes, and Barriers Among Indian Oncologists and Gynecologists.
J Adolesc Young Adult Oncol. 2020 May 22;:
Authors: Tholeti P, Uppangala S, Bhat V, Udupa KS, Kumar V, Patted S, Natarajan P, Spears N, Kalthur G, Woodruff TK, Adiga SK
Abstract
Purpose: Recommendations from the American Society of Clinical Oncology…
Development of Human Ectocervical Tissue Models with Physiologic Endocrine and Paracrine Signaling.
Biol Reprod. 2020 May 13;:
Authors: McKinnon KE, Sensharma R, Williams C, Ravix J, Getsios S, Woodruff TK
Abstract
There is a shortage of research models that adequately represent the unique mucosal environment of human ectocervix, limiting development of…
Ovarian tissue cryopreservation as standard of care: what does this mean for pediatric populations?
J Assist Reprod Genet. 2020 May 11;:
Authors: Nahata L, Woodruff TK, Quinn GP, Meacham LR, Chen D, Appiah LC, Finlayson C, Orwig KE, Laronda MM, Rowell EE, Anazodo A, Frias O, Rios JS, Whiteside S, Gomez-Lobo V, Dwiggins M, Childress KJ, Hoefgen…
Author Correction: Engineered reproductive tissues.
Nat Biomed Eng. 2020 Apr 24;:
Authors: Gargus ES, Rogers HB, McKinnon KE, Edmonds ME, Woodruff TK
Abstract
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
…
Distinct follicular and luteal transcriptional profiles in engineered human ectocervical tissue dependent on menstrual cycle phase.
Biol Reprod. 2020 Apr 21;:
Authors: McKinnon KE, Getsios S, Woodruff TK
Abstract
To investigate genomic pathways that may influence physiology and infectivity during the menstrual cycle, RNA sequence analysis was performed on patient-matched engineered…
Survey of Fertility Preservation Options Available to Patients With Cancer Around the Globe.
JCO Glob Oncol. 2020;6:
Authors: Rashedi AS, de Roo SF, Ataman LM, Edmonds ME, Silva AA, Scarella A, Horbaczewska A, Anazodo A, Arvas A, Ramalho de Carvalho B, Sartorio C, Beerendonk CCM, Diaz-Garcia C, Suh CS, Melo C, Yding Andersen C, Motta E, Greenblatt…
Building Oncofertility Core Competency in Developing Countries: Experience From Egypt, Tunisia, Brazil, Peru, and Panama.
JCO Glob Oncol. 2020;6:
Authors: Salama M, Ataman L, Taha T, Azmy O, Braham M, Douik F, Khrouf M, Rodrigues JK, Reis FM, Sánchez F, Romero S, Vega M, Woodruff TK
Abstract
Purpose: Little is known…
Barriers and Opportunities of Oncofertility Practice in Nine Developing Countries and the Emerging Oncofertility Professional Engagement Network.
JCO Glob Oncol. 2020;6:
Authors: Salama M, Ataman-Millhouse L, Sobral F, Terrado G, Scarella A, Bourlon MT, Adiga SK, Udupa KS, Mahajan N, Patil M, Venter C, Demetriou G, Quintana R, Rodriguez G, Quintana T, Viale L, Bonilla YAR, Noguera…
Survey of Third-Party Parenting Options Associated With Fertility Preservation Available to Patients With Cancer Around the Globe.
JCO Glob Oncol. 2020;6:
Authors: Rashedi AS, de Roo SF, Ataman LM, Edmonds ME, Silva AA, Scarella A, Horbaczewska A, Anazodo A, Arvas A, Ramalho de Carvalho B, Sartorio C, Beerendonk CCM, Diaz-Garcia C, Suh CS, Melo C, Andersen CY,…
Engineered reproductive tissues.
Nat Biomed Eng. 2020 Apr 06;:
Authors: Gargus ES, Rogers HB, McKinnon KE, Edmonds ME, Woodruff TK
Abstract
Engineered male and female biomimetic reproductive tissues are being developed as autonomous in vitro units or as integrated multi-organ in vitro systems to support germ cell and embryo function, and…
Oncofertility as a Universal Right and a Global Oncology Priority.
JCO Glob Oncol. 2020 Mar;6:314-316
Authors: Bourlon MT, Anazodo A, Woodruff TK, Segelov E
PMID: 32119579 [PubMed - as supplied by publisher]
Zinc exocytosis is sensitive to myosin light chain kinase inhibition in mouse and human eggs.
Mol Hum Reprod. 2020 Mar 02;:
Authors: Lee HC, Edmonds ME, Duncan FE, O'Halloran TV, Woodruff TK
Abstract
Zinc dynamics are essential for oocyte meiotic maturation, egg activation, and preimplantation embryo development. During fertilisation and egg…
Tell Me Your Superpower!
Endocrinology. 2020 Feb 22;:
Authors: Woodruff TK
PMID: 32087084 [PubMed - as supplied by publisher]
Lessons from bioengineering the ovarian follicle: a personal perspective.
Reproduction. 2019 Dec;158(6):F113-F126
Authors: Woodruff TK
Abstract
The ovarian follicle and its maturation captivated my imagination and inspired my scientific journey - what we know now about this remarkable structure is captured in this invited review. In the past decade, our knowledge…
Lifting Life's Little Anchors: The Latitude and Longitude of Science.
Endocrinology. 2019 Dec 01;160(12):2861-2862
Authors: Woodruff TK
PMID: 31712827 [PubMed - in process]
Preserving fertility in female patients with hematological malignancies: a multidisciplinary oncofertility approach.
Ann Oncol. 2019 Nov;30(11):1760-1775
Authors: Salama M, Anazodo A, Woodruff TK
Abstract
Oncofertility is a new interdisciplinary field at the intersection of oncology and reproductive medicine that expands fertility options for young cancer patients. The most common forms of…
Inside, Outside, Upside Down.
Endocrinology. 2019 Nov 01;160(11):2618-2619
Authors: Woodruff TK
PMID: 31617895 [PubMed - in process]
Scaffold-free endometrial organoids respond to excess androgens associated with polycystic ovarian syndrome.
J Clin Endocrinol Metab. 2019 Oct 16;:
Authors: Wiwatpanit T, Murphy AR, Lu Z, Urbanek M, Burdette JE, Woodruff TK, Kim JJ
Abstract
CONTEXT: Polycystic ovary syndrome (PCOS) is a prevalent disorder in reproductive aged women associated with a…