Construction and Bioengineering of Human Bioprosthetic Ovaries from Cryopreserved Ovarian Tissue
Int J Mol Sci. 2025 Jun 10;26(12):5545
Authors: Cao M, Todorov P, Rahimi G, Salama M, Woodruff TK, Isachenko E, Skala C, Isachenko V
Abstract:
Ovarian tissue cryopreservation is increasingly recognized as an effective fertility preservation option for cancer patients undergoing gonadotoxic therapies. After cancer treatment, transplantation of frozen-thawed…
Inorganic profiles of preimplantation embryos reveal a role for zinc in blastocyst development
bioRxiv [Preprint]. 2025 May 18:2025.05.14.654061
Authors: Balough JL, O'Halloran TV, Duncan FE, Woodruff TK
Abstract:
Elements such as iron, copper and zinc play essential roles in the mammalian oocyte, egg, and embryo, however among these metals, zinc plays unique regulatory roles. Temporal fluctuations in zinc concentrations drive…