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Lessons from bioengineering the ovarian follicle: a personal perspective.

Lessons from bioengineering the ovarian follicle: a personal perspective. Reproduction. 2019 Dec;158(6):F113-F126 Authors: Woodruff TK Abstract The ovarian follicle and its maturation captivated my imagination and inspired my scientific journey - what we know now about this remarkable structure is captured in this invited review. In the past decade, our knowledge…

Preserving fertility in female patients with hematological malignancies: a multidisciplinary oncofertility approach.

Preserving fertility in female patients with hematological malignancies: a multidisciplinary oncofertility approach. Ann Oncol. 2019 Nov;30(11):1760-1775 Authors: Salama M, Anazodo A, Woodruff TK Abstract Oncofertility is a new interdisciplinary field at the intersection of oncology and reproductive medicine that expands fertility options for young cancer patients. The most common forms of…

Scaffold-free endometrial organoids respond to excess androgens associated with polycystic ovarian syndrome.

Scaffold-free endometrial organoids respond to excess androgens associated with polycystic ovarian syndrome. J Clin Endocrinol Metab. 2019 Oct 16;: Authors: Wiwatpanit T, Murphy AR, Lu Z, Urbanek M, Burdette JE, Woodruff TK, Kim JJ Abstract CONTEXT: Polycystic ovary syndrome (PCOS) is a prevalent disorder in reproductive aged women associated with a…

Preserving fertility in female patients with hematological malignancies: A multidisciplinary oncofertility approach.

Preserving fertility in female patients with hematological malignancies: A multidisciplinary oncofertility approach. Ann Oncol. 2019 Aug 16;: Authors: Salama M, Anazodo A, Woodruff TK Abstract Oncofertility is a new interdisciplinary field at the intersection of oncology and reproductive medicine that expands fertility options for young cancer patients. The most common forms…

Words To Work By.

Words To Work By. Endocrinology. 2019 Aug 01;160(8):1830-1831 Authors: Woodruff TK PMID: 31313821 [PubMed - in process]

Poorly-Controlled Type 1 Diabetes Mellitus Impairs LH-LHCGR Signaling in the Ovaries and Decreases Female Fertility in Mice.

Poorly-Controlled Type 1 Diabetes Mellitus Impairs LH-LHCGR Signaling in the Ovaries and Decreases Female Fertility in Mice. Yonsei Med J. 2019 Jul;60(7):667-678 Authors: Lee J, Lee HC, Kim SY, Cho GJ, Woodruff TK Abstract PURPOSE: The aim of this study was to investigate how type I diabetes mellitus (T1D) affects the…

Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development.

Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development. BMC Bioinformatics. 2019 Jun 10;20(1):307 Authors: Peñalver Bernabé B, Thiele I, Galdones E, Siletz A, Chandrasekaran S, Woodruff TK, Broadbelt LJ, Shea LD Abstract BACKGROUND: The maturation of the female germ cell, the oocyte, requires…

FertiPROTEKT, Oncofertility Consortium and the Danish Fertility-Preservation Networks – What Can We Learn From Their Experiences?

FertiPROTEKT, Oncofertility Consortium and the Danish Fertility-Preservation Networks - What Can We Learn From Their Experiences? Clin Med Insights Reprod Health. 2019;13:1179558119845865 Authors: von Wolff M, Andersen CY, Woodruff TK, Nawroth F Abstract Fertility preservation is an increasingly important discipline. It requires close coordination between reproductive medicine specialists, reproductive biologists, and…

Factors Affecting Fertility Decision-Making Among Transgender Adolescents and Young Adults.

Factors Affecting Fertility Decision-Making Among Transgender Adolescents and Young Adults. LGBT Health. 2019 Apr;6(3):107-115 Authors: Chen D, Kyweluk MA, Sajwani A, Gordon EJ, Johnson EK, Finlayson CA, Woodruff TK Abstract PURPOSE: This study aimed to identify factors affecting transgender adolescents' and young adults' (AYA) decisions to pursue fertility preservation (FP). …