Promoting extracellular matrix remodeling via ascorbic acid enhances the survival of primary ovarian follicles encapsulated in alginate hydrogels.
Biotechnol Bioeng. 2013 Dec 30;
Authors: Tagler D, Makanji Y, Tu T, Peñalver Bernabé B, Lee R, Zhu J, Kniazeva E, Hornick JE, Woodruff TK, Shea LD
Abstract
The in vitro growth of…
Primate Follicular Development and Oocyte Maturation In Vitro.
Adv Exp Med Biol. 2013;761:43-67
Authors: Xu J, Xu M, Bernuci MP, Fisher TE, Shea LD, Woodruff TK, Zelinski MB, Stouffer RL
Abstract
The factors and processes involved in primate follicular development are complex and not fully understood. An encapsulated three-dimensional (3D) follicle…
Human Ovarian Tissue Cortex Surrounding Benign and Malignant Lesions.
Reprod Sci. 2013 Oct 4;
Authors: Pavone ME, Hirshfeld-Cytron J, Tingen C, Thomas C, Thomas J, Lowe MP, Schink JC, Woodruff TK
Abstract
Objective:To quantify the number of follicles in patients with ovarian pathologies, benign and malignant, in pregnant and nonpregnant states…
Involvement of androgens in ovarian health and disease.
Mol Hum Reprod. 2013 Sep 10;
Authors: Lebbe M, Woodruff TK
Abstract
In women, ovary and adrenal gland produce androgens. Androgens are essential drivers of the primordial to antral follicle development, prior to serving as substrate for estrogen production in the later stages…
Reproductive endocrinology: Fertility in female survivors of childhood cancer.
Nat Rev Endocrinol. 2013 Sep 3;
Authors: Woodruff TK
PMID: 23999232 [PubMed - as supplied by publisher]
From the bench to bedside to babies: translational medicine made possible by funding multidisciplinary team science.
J Assist Reprod Genet. 2013 Aug 23;
Authors: Woodruff TK
Abstract PURPOSE: In 2005, The National Institutes of Health (NIH) called upon the scientific community to identify the most intractable problems in science and…
Bioengineering the Ovarian Follicle Microenvironment.
Annu Rev Biomed Eng. 2013 Aug 22;
Authors: Shea LD, Woodruff TK, Shikanov A
Abstract
Chemo- and radiation therapies used to treat cancer can have the unintended effect of making patients infertile. Clinically established fertility preservation methods, such as egg and embryo cryopreservation, are not applicable…
Three-dimensional systems for in vitro follicular culture: overview of alginate-based matrices.
Reprod Fertil Dev. 2013 Jul 19;
Authors: Brito IR, Lima IM, Xu M, Shea LD, Woodruff TK, Figueiredo JR
PMID: 23866836 [PubMed - as supplied by publisher]
Supplemented αMEM/F12-based medium enables the survival and growth of primary ovarian follicles encapsulated in alginate hydrogels.
Biotechnol Bioeng. 2013 Jun 25;
Authors: Tagler D, Makanji Y, Anderson NR, Woodruff TK, Shea LD
Abstract Hydrogel-encapsulating culture systems for ovarian follicles support the in vitro growth of secondary follicles from various species…
Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network.
Cell Death Differ. 2013 Apr 19;
Authors: Kim SY, Cordeiro MH, Serna VA, Ebbert K, Butler LM, Sinha S, Mills AA, Woodruff TK, Kurita T
Abstract Non-proliferating oocytes within avascular regions of the ovary…
Future Directions in Oncofertility and Fertility Preservation: A Report from the 2011 Oncofertility Consortium Conference.
J Adolesc Young Adult Oncol. 2013 Mar;2(1):25-30
Authors: Waimey KE, Duncan FE, Su HI, Smith K, Wallach H, Jona K, Coutifaris C, Gracia CR, Shea LD, Brannigan RE, Chang RJ, Zelinski MB, Stouffer RL, Taylor RL, Woodruff TK
Abstract …
Detection and quantification of maternal-effect gene transcripts in mouse second polar bodies: potential markers of embryo developmental competence.
Fertil Steril. 2013 Mar 2;
Authors: Jiao ZX, Woodruff TK
Abstract OBJECTIVE: To test the hypothesis that quantification of messenger RNAs originating from the second polar body (PB2) provides a noninvasive tool…
Recreating the female reproductive tract in vitro using iPSC technology in a linked microfluidics environment.
Stem Cell Res Ther. 2013;4 Suppl 1:S13
Authors: Laronda MM, Burdette JE, Kim J, Woodruff TK
Abstract
The female reproductive tract produces hormones for reproductive function and cardiovascular, bone and sexual health; the tract supplies a…
Imaging and elemental mapping of biological specimens with a dual-EDS dedicated scanning transmission electron microscope.
Ultramicroscopy. 2013 Feb 4;128C:24-31
Authors: Wu JS, Kim AM, Bleher R, Myers BD, Marvin RG, Inada H, Nakamura K, Zhang XF, Roth E, Li SY, Woodruff TK, O'Halloran TV, Dravid VP
Abstract A dedicated analytical…
Follicle microenvironment-associated alterations in gene expression in the mouse oocyte and its polar body.
Fertil Steril. 2013 Jan 8;
Authors: Jiao ZX, Woodruff TK
Abstract OBJECTIVE: To determine whether the follicle environment modulates oocyte-specific gene transcript levels in cultured oocytes and polar bodies (PBs). DESIGN: Animal study. SETTING: Large academic…
Nano-Encapsulation of Arsenic Trioxide Enhances Efficacy against Murine Lymphoma Model while Minimizing Its Impact on Ovarian Reserve In Vitro and In Vivo.
PLoS One. 2013;8(3):e58491
Authors: Ahn RW, Barrett SL, Raja MR, Jozefik JK, Spaho L, Chen H, Bally MB, Mazar AP, Avram MJ, Winter JN, Gordon LI, Shea LD, O'Halloran TV, Woodruff TK
Abstract
Advances in cancer therapy…
Correction: The Possible Role of Resource Requirements and Academic Career-Choice Risk on Gender Differences in Publication Rate and Impact.
PLoS One. 2013;8(5)
Authors: Duch J, Zeng XH, Sales-Pardo M, Radicchi F, Otis S, Woodruff TK, Nunes Amaral LA
Abstract
[This corrects the article on p. e51332 in vol. 7.].
PMID: 23704866 [PubMed - as supplied by publisher]