Closing the loop on female fertility
Sci Adv. 2021 Dec 17;7(51):eabn1373
Author: Woodruff TK
Abstract:
Discovery of a previously unidentified pituitary protein could provide innovative therapeutic options to regulate female fertility.
doi: 10.1126/sciadv.abn1373. Epub 2021 Dec 15. PMID: 34910506; PMCID: PMC11323799.
A platform utilizing Drosophila ovulation for nonhormonal contraceptive screening
Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2026403118
Authors: Jiang K, Zhang J, Huang Y, Wang Y, Xiao S, Hadden MK, Woodruff TK, Sun J
Abstract:
A significant unmet need for new contraceptive options for both women and men remains due to side-effect profiles, medical concerns, and the inconvenience of many…
Metal ion fluxes controlling amphibian fertilization
Nat Chem. 2021 Jul;13(7):683-691
Authors: Seeler JF, Sharma A, Zaluzec NJ, Bleher R, Lai B, Schultz EG, Hoffman BM, LaBonne C, Woodruff TK, O'Halloran TV
Abstract:
Mammalian oocytes undergo major changes in zinc content and localization to be fertilized, the most striking being the rapid exocytosis of over 10 billion zinc ions in what…
Dental resins used in 3D printing technologies release ovo-toxic leachates
Chemosphere. 2021 May;270:129003
Authors: Rogers HB, Zhou LT, Kusuhara A, Zaniker E, Shafaie S, Owen BC, Duncan FE, Woodruff TK
Abstract:
We recently engineered the first female reproductive tract on a chip (EVATAR), to enable sex-based ex vivo research. To increase the scalability and accessibility of EVATAR, we turned to…
Fallopian Tube-Derived Tumor Cells Induce Testosterone Secretion from the Ovary, Increasing Epithelial Proliferation and Invasion
Cancers (Basel). 2021 Apr 16;13(8):1925
Authors: Colina JA, Zink KE, Eliadis K, Salehi R, Gargus ES, Wagner SR, Moss KJ, Baligod S, Li K, Kirkpatrick BJ, Woodruff TK, Tsang BK, Sanchez LM, Burdette JE
Abstract:
The fallopian tube epithelium is the site of origin for…
Reply: Exposure of human fallopian tube epithelium to elevated testosterone results in alteration of cilia gene expression and beating
Hum Reprod. 2021 May 17;36(6):1725
Authors: Jackson-Bey T, Colina J, Isenberg BC, Coppeta J, Urbanek M, Kim JJ, Woodruff TK, Burdette JE, Russo A
doi: 10.1093/humrep/deab022. PMID: 33575737; PMCID: PMC8599863.
Installing oncofertility programs for common cancers in optimum resource settings (Repro-Can-OPEN Study Part II): a committee opinion
J Assist Reprod Genet. 2021 Jan;38(1):163-176
Authors: Practice Committee of the Oncofertility Consortium
Abstract:
Purpose: The main objective of Repro-Can-OPEN Study Part 2 is to learn more about oncofertility practices in optimum resource settings to provide a roadmap to establish oncofertility best practice models.
Methods: As…
A View from the Past into our Collective Future: the Oncofertility Consortium Vision Statement
J Assist Reprod Genet. 2021 Jan;38(1):3-15
Authors: Woodruff TK, Ataman-Millhouse L, Acharya KS, Almeida-Santos T, Anazodo A, Anderson RA, Appiah L, Bader J, Becktell K, Brannigan RE, Breech L, Bourlon MT, Bumbuliene Ž, Burns K, Campo-Engelstein L, Campos JR, Centola GM, Chehin MB, Chen…