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Toward Sex Inclusivity: Perspectives on Sex as a Biological Variable

Toward Sex Inclusivity: Perspectives on Sex as a Biological Variable J Womens Health (Larchmt). 2025 Jul 7. Authors: Mulles SM, Aziz DZ, Binion CC, Pai N, Maragos SL, Flattum ME, Kowalczyk M, Volerman A, Woodruff TK, Kibbe MR. Abstract: Purpose: The National Institutes of Health (NIH) policy on sex as a biological variable (SABV) was implemented in 2016 to encourage researchers…

Construction and Bioengineering of Human Bioprosthetic Ovaries from Cryopreserved Ovarian Tissue

Construction and Bioengineering of Human Bioprosthetic Ovaries from Cryopreserved Ovarian Tissue Int J Mol Sci. 2025 Jun 10;26(12):5545 Authors: Cao M, Todorov P, Rahimi G, Salama M, Woodruff TK, Isachenko E, Skala C, Isachenko V Abstract: Ovarian tissue cryopreservation is increasingly recognized as an effective fertility preservation option for cancer patients undergoing gonadotoxic therapies. After cancer treatment, transplantation of frozen-thawed…

Inorganic profiles of preimplantation embryos reveal a role for zinc in blastocyst development

Inorganic profiles of preimplantation embryos reveal a role for zinc in blastocyst development bioRxiv [Preprint]. 2025 May 18:2025.05.14.654061 Authors: Balough JL, O'Halloran TV, Duncan FE, Woodruff TK Abstract: Elements such as iron, copper and zinc play essential roles in the mammalian oocyte, egg, and embryo, however among these metals, zinc plays unique regulatory roles. Temporal fluctuations in zinc concentrations drive…