Hope, hypothesis, and the inhibin receptor. Does specific inhibin binding suggest there is a specific inhibin receptor?
Endocrinology. 1999 Jan;140(1):3-5
Authors: Woodruff TK
PMID: 9886799 [PubMed - indexed for MEDLINE]
Identification of naturally occurring follistatin complexes in human biological fluids.
Biol Reprod. 1999 Jan;60(1):8-13
Authors: Wang EY, Draper LB, Lee E, Polak A, Sluss P, Weiss J, Woodruff TK
Follistatin (FS) binds activin and inhibin proteins. Many organs are sensitive to activin and inhibin; thus the formation of FS-activin/inhibin complexes is important to our understanding of ligand activity.…
Editorial: Hope, Hypothesis, and the Inhibin Receptor. Does Specific Inhibin Binding Suggest There Is a Specific Inhibin Receptor?
Endocrinology. 1999 Jan 01;140(1):3-5
Authors: Woodruff TK
PMID: 28200576 [PubMed]
Regulation of cellular and system function by activin.
Biochem Pharmacol. 1998 Apr 1;55(7):953-63
Authors: Woodruff TK
Activin is an important molecule that regulates hormonogenesis, cellular homeostasis (divide or die pathways), and differentiation programs (developmentally and in adult cells). The cellular mechanisms that integrate an activin signal into a physiological response include a binary receptor complex and tandem serine…
Cellular localization of mRNA and protein: in situ hybridization histochemistry and in situ ligand binding.
Methods Cell Biol. 1998;57:333-51
Authors: Woodruff TK
Powerful methods for the detection of mRNA and proteins in cells and tissue sections have been developed since the mid-1980s. This chapter discusses the applications of in situ hybridization histochemistry and in situ ligand binding to…
Identification of an inhibin receptor in gonadal tumors from inhibin alpha-subunit knockout mice.
J Biol Chem. 1998 Jan 2;273(1):398-403
Authors: Draper LB, Matzuk MM, Roberts VJ, Cox E, Weiss J, Mather JP, Woodruff TK
Inhibins and activins are dimeric proteins that are functional antagonists and are structurally related to the transforming growth factor-beta (TGFbeta) family of growth and…
Role of androgens in testicular tumor development in inhibin-deficient mice.
Endocrinology. 1997 Nov;138(11):5000-5
Authors: Shou W, Woodruff TK, Matzuk MM
To understand gonadal tumor development, we have previously created a mouse model in which mice deficient in the inhibins develop gonadal sex cord-stromal tumors with essentially 100% penetrance. These tumors develop as early as 4 weeks of age…
High levels of fetal membrane activin beta A and activin receptor IIB mRNAs and augmented concentration of amniotic fluid activin A in women in term or preterm labor.
J Endocrinol. 1997 Jul;154(1):95-101
Authors: Petraglia F, Di Blasio AM, Florio P, Gallo R, Genazzani AR, Woodruff TK, Vale W
The aim of the present study was to evaluate whether…