Regulation of inhibin synthesis in the rat ovary
Annu Rev Physiol. 1990;52:807-21
Authors: Woodruff TK, Mayo KE
Abstract:
The lifespan of the female rodent is characterized by dynamic changes in the hormonal regulation of the reproductive axis. From the time ovarian follicular growth is initiated in peripubertal animals, through recruitment, ovulation and luteinization during the estrous cycle, to the quiescent…
Decreased inhibin gene expression in preovulatory follicles requires primary gonadotropin surges
Endocrinology. 1989 May;124(5):2193-9
Authors: Woodruff TK, D'Agostino J, Schwartz NB, Mayo KE
Abstract:
We have examined the role of the primary gonadotropin surges in regulating inhibin alpha- and beta A-subunit mRNA levels in rat ovarian follicles. Inhibin subunit mRNA levels decline dramatically on the evening of proestrus in follicles…
Unilateral ovariectomy increases inhibin messenger ribonucleic acid levels in newly recruited follicles
Endocrinology. 1989 Jan;124(1):310-7
Authors: D'Agostino J, Woodruff TK, Mayo KE, Schwartz NB
Abstract:
We have used the unilaterally ovariectomized (ULO) rat as an experimental model to assess transient relationships between follicular recruitment and inhibin mRNA levels in the ovary. Animals were divided into three experimental groups (ULO, sham-operated,…
Dynamic changes in inhibin messenger RNAs in rat ovarian follicles during the reproductive cycle
Science. 1988 Mar 11;239(4845):1296-9
Authors: Woodruff TK, D'Agostino J, Schwartz NB, Mayo KE
Abstract:
The alterations in morphology and function of the ovarian follicle as it matures, ovulates, and becomes a corpus luteum are dramatic. A variety of steroid and polypeptide hormones influence these processes, and…
Rat inhibin: molecular cloning of alpha- and beta-subunit complementary deoxyribonucleic acids and expression in the ovary
Mol Endocrinol. 1987 Aug;1(8):561-8
Authors: Woodruff TK, Meunier H, Jones PB, Hsueh AJ, Mayo KE
Abstract:
Inhibin is a gonadal protein hormone that suppresses the secretion of FSH from pituitary gonadotrophs. It has previously been characterized as a heterodimer of two dissimilar subunits (alpha,…
mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence
Mol Cell Biol. 1986 Aug;6(8):2932-43
Authors: Adam SA, Nakagawa T, Swanson MS, Woodruff TK, Dreyfuss G
Abstract:
We identified and produced antibodies to the major proteins that interact with poly(A)+ RNAs in the yeast Saccharomyces cerevisiae. The major proteins which were cross-linked by UV light to…